Cover Picture: Pillar[5]arene-Based Glycoclusters: Synthesis and Multivalent Binding to Pathogenic Bacterial Lectins (Chem. Eur. J. 9/2016)

The potential therapeutic applications of multivalent glycoclusters targeting bacterial adhesion lectins call for the design of core scaffolds presenting various valency and topologies to understand the specificities of binding. Pillar[5]arenes are ideal candidates in this endeavor. More information...

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Veröffentlicht in:Chemistry : a European journal 2016-02, Vol.22 (9), p.2833-2833
Hauptverfasser: Buffet, Kevin, Nierengarten, Iwona, Galanos, Nicolas, Gillon, Emilie, Holler, Michel, Imberty, Anne, Matthews, Susan E., Vidal, Sébastien, Vincent, Stéphane P., Nierengarten, Jean-François
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Sprache:eng
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Zusammenfassung:The potential therapeutic applications of multivalent glycoclusters targeting bacterial adhesion lectins call for the design of core scaffolds presenting various valency and topologies to understand the specificities of binding. Pillar[5]arenes are ideal candidates in this endeavor. More information can be found in the Full Paper by A. Imberty, S. Vidal, S. P. Vincent, J.‐F. Nierengarten, et al. on page 2955 ff.
ISSN:0947-6539
1521-3765
DOI:10.1002/chem.201600405