Back Cover: Imaging Glycosylation In Vivo by Metabolic Labeling and Magnetic Resonance Imaging (Angew. Chem. Int. Ed. 4/2016)
Cell‐surface glycans were imaged in live mice by magnetic resonance imaging, following metabolic labeling with an azido sugar and subsequent bioorthogonal reaction with a strained cyclooctyne linked to a gadolinium contrast agent. In their Communication on page 1286 ff., A. A. Neves et al. show that...
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Veröffentlicht in: | Angewandte Chemie International Edition 2016-01, Vol.55 (4), p.1566-1566 |
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creator | Neves, André A. Wainman, Yéléna A. Wright, Alan Kettunen, Mikko I. Rodrigues, Tiago B. McGuire, Sarah Hu, De-En Bulat, Flaviu Geninatti Crich, Simonetta Stöckmann, Henning Leeper, Finian J. Brindle, Kevin M. |
description | Cell‐surface glycans were imaged in live mice by magnetic resonance imaging, following metabolic labeling with an azido sugar and subsequent bioorthogonal reaction with a strained cyclooctyne linked to a gadolinium contrast agent. In their Communication on page 1286 ff., A. A. Neves et al. show that significant azido sugar dependent contrast was observed in various tissues two hours after administration of the contrast agent. |
doi_str_mv | 10.1002/anie.201511259 |
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subjects | bioorthogonal chemistry cancer Cell surface Gadolinium glycans Glycosylation Labeling Magnetic resonance imaging Marking Metabolism NMR Nuclear magnetic resonance Polysaccharides Sugar |
title | Back Cover: Imaging Glycosylation In Vivo by Metabolic Labeling and Magnetic Resonance Imaging (Angew. Chem. Int. Ed. 4/2016) |
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