Frontispiece: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere

Bioisosteres In their Communication on page 3580 ff., C. M. Williams, G. P. Savage, J. Tsanaktsidis et al. confirm that cubane can act as a benzene bioisostere by synthesizing and evaluating cubane derivatives of five biologically important molecules.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Angewandte Chemie International Edition 2016-03, Vol.55 (11), p.n/a
Hauptverfasser:	Chalmers, Benjamin A., Xing, Hui, Houston, Sevan, Clark, Charlotte, Ghassabian, Sussan, Kuo, Andy, Cao, Benjamin, Reitsma, Andrea, Murray, Cody-Ellen P., Stok, Jeanette E., Boyle, Glen M., Pierce, Carly J., Littler, Stuart W., Winkler, David A., Bernhardt, Paul V., Pasay, Cielo, De Voss, James J., McCarthy, James, Parsons, Peter G., Walter, Gimme H., Smith, Maree T., Cooper, Helen M., Nilsson, Susan K., Tsanaktsidis, John, Savage, G. Paul, Williams, Craig M.
Format:	Artikel
Sprache:	eng
Schlagworte:	agrochemicals Benzene bioisosteres Chemical synthesis Cubane Hydrocarbons pharmaceuticals structure-activity relationships
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Bioisosteres In their Communication on page 3580 ff., C. M. Williams, G. P. Savage, J. Tsanaktsidis et al. confirm that cubane can act as a benzene bioisostere by synthesizing and evaluating cubane derivatives of five biologically important molecules.
ISSN:	1433-7851 1521-3773
DOI:	10.1002/anie.201681161