FRI0345 Neurological Manifestations of Primary Sjögren Syndrome

BackgroundPrimary Sjögren syndrome (pSS) is a chronic systemic autoimmune disease with a relevant impact in patients' quality of life. Neurological manifestations of pSS could have an important impact on morbidity and mortality.ObjectivesThe aim of our study was to evaluate central and peripheral neurological manifestations of a pSS cohort of patients assisted in Spanish Reumathology Departments.MethodsThis is a multicentre descriptive transversal study of pSS patients from thirty-three rheumatology departments. Patients fulfilling European/American consensus criteria were included after randomisation. By reviewing clinical records and interviewing the patients, we collected epidemiological, clinical, serologic, therapeutic, and disease activity indexes data. Informed consent was obtained and local ethics committees approved the study. Variables were analysed by descriptive statistical methods, using means, medians, and rates. Chi-square was used to establish the statistical associations, being considered a p