SAT0129 Vitamin D Status and Its Association with Disease Activity, Severity and Physical Disability in Rheumatoid Arthritis Patients

BackgroundVitamin D has immunomodulatory effects in a wide range of human autoimmune diseases; including Rheumatoid Arthritis (RA). Vitamin D deficiency is common in RA.ObjectivesThe objective of this study was to evaluate vitamin D status in RA patients and assess the relationship between vitamin D levels, disease activity, severity and physical disability.MethodsWe included in this cross-sectional study patients with RA according to ACR/EULAR classification criteria, followed up at the Department of Rheumatology. Demographic characteristics and disease specific variables were collected. Disease activity was assessed by the Disease Activity Score (DAS 28). Functional disability was evaluated by the Health Assessment Questionnaire (HAQ). Joint destruction was assessed by the van der Heijde-modified Sharp Score. Serum concentrations of 25(OH) Vitamin D were measured. According to the GRIO recommendations, 25(OH)D insufficiency was defined as 25(OH)D ranging from 10 to 30 ng/mL, and deficiency as 25(OH)D