AB0436 All The “Hispanics” Are Not Equal. The Severity and Activity of Patients with SLE Is Higher in Mestizos Latin American vs. European Caucasian. Lessons from Relesser

BackgroundSLE is a known disease for the study of ethnic and gender minorities. In Spain, from 1998 to 2011, occurred a significant immigration from Latin American people. The English speakers consider “Hispanics” as the same ethnic group. But there are differences between the Hispanics from Spain (with ethnicity European Caucasian) and the Hispanics from Latin America (with ethnicity Mestizo Latin American).ObjectivesTo know the demographic, clinical, severity, activity, damage, mortality and comorbidity of SLE in Hispanics with ethnicity European Caucasian (EC) and in Hispanic Mestizos from Latin American (MLA) residents in Spain. To identify differences between the groups.MethodsDesign: observational, multicentric, crossover study. Patients with SLE (ACR 1987) and 3) OR 1,45 (1,038 – 2, 026, p=0,02. This differences were not found for activity: OR 0,98 (0.30 - 1.66), may be for collinearity.Table 1VariableEuropean CaucasianMestizos Latin Americanpn, %n, %Total3.305, 92185, 5Women2.891, 90176, 950.02Myositis113, 315, 80.001Hemolytic anemia271, 824. 140.01Lupus nephritis952, 2979, 44