AB0923 Prevalence of Rheumatologic Symptoms and Specific Rheumatic Diseases in Patients with History of Breast Implants

BackgroundThe Autoimmune Syndrome Induced by Adjuvant (ASIA) includes several clinical conditions as siliconosis, gulf war syndrome, miofasciitis macrophagic syndrome and post vaccination phenomenon. Acting as an adjuvant the Breast implants (BI) could be potentially linked with several autoimmune diseases.ObjectivesThe purpose of this study was to describe the rheumatological characteristics of a group of patients with the history of previous BI, that assisted to a rheumatologist, and to compare them with age matched controls.MethodsA retrospective, descriptive study was designed. Patients with the history of BI, that assisted to a rheumatologist, where included. The data was collected from clinical registries, including socio-demographic data and comorbidities, kind and duration of symptoms, development of a specific rheumatologic syndrome/disease, fulfilment of ASIA proposed criteria and type of clinical evolution. All the patients and their controls attended private practice rheumatology outpatient clinics.For each case, 2 controls were randomly selected from clinical registries if they had: ±2 years of age compared with the cases at the first visit, had no history of BI or pre-existing rheumatological disease and had attended at least 2 followup visits.Statistical Analysis – Categorical data were expressed in frequency and percentage, continuous data in median and interquartile range (IQR). Chi2 and Fisher test were used to analyse categorical data and Student T test or Mann-Whitney for continuous data based in its distribution. A p value