FRI0651-HPR Three Year Trends in Physical Activity in Adults with Rheumatoid Arthritis

BackgroundAdults with Rheumatoid Arthritis (RA) demonstrate low physical activity (PA) levels and excess cardiovascular risk. Most PA studies in RA are cross-sectional and PA interventions are often part of self-management programs of short-term duration (≤1 year). Longitudinal examination of PA in RA may inform PA intervention design.ObjectivesTo identify trends in PA in adults with RA over 3 years and to longitudinally characterize correlates of PA.MethodsThis 3-yr study included 573 RA registry patients with ≥1 annual visit and complete PA data. Baseline and annual measures were: demographics, medical history/meds, alcohol use, psychosocial support, self-efficacy, disease activity, quality of life, patient/physician global assessment, function, and PA defined as either meeting or not meeting the US Dept Health & Human Services (DHHS) recommendations of 150 min of moderate activity/wk or 90 min vigorous PA/week, at each interval. McNemar χ2 tests assessed the relationship between disease activity (DAS-CRP3 categories) and PA. A mixed model repeated measures analysis identified factors associated with PA, adjusting for disease activity over time.Results94% of adults were Caucasian, 83% female with a mean age of 61 yrs (SD=12). Average RA duration was 19.5 yrs (SD=11.8). At baseline, 59.2% had low disease activity, 29.9% moderate and 10.9% highly active disease. 36% of subjects were sedentary and 29% met the PA recommendations. Over 3 years, PA was significantly negatively associated with disease activity (χ2, p53–62 OR=0.62; 95%CI 0.40,0.94; age >62–69 OR=0.64; 95%CI 0.42,0.96; age >69 OR=0.53; 95%CI 0.33,0.83) poor mental health (OR =0.58; 95%CI 0.38,0.87) and higher patient global assessment scores [10–20] OR=0.59; 95%CI 0.41,0.85; [>20–50] OR=0.61; 95%CI 0.39,0.96; [>50] OR=0.51; 95%CI 0.29,0.89) were associated with not meeting the PA threshold.ConclusionsA small proportion of adults with RA met PA recommendations, despite well-controlled disease, and the proportion decreased over time. After controlling for disease activity, modifiable correlates of PA were linked to lifestyle, mental health and patient perceptions of disease, suggesting PA interventions target patient perspectives and lifestyl