SAT0060 Orthopaedic Surgery in an Asian Rheumatoid Arthritis Cohort: Predictors and Impact on Quality of Life

ObjectivesTo identify predictors of orthopaedic surgery and its impact on quality of life in a South-East Asian rheumatoid arthritis registry cohort.MethodsData was collected from patients enrolled in the Tan Tock Seng Hospital Rheumatoid Arthritis Registry. All patients fulfilled the 1987 ACR criteria for RA. The clinical, extraarticular features (EAF), disease activity score (DAS 28), functional status (Health Assessment Questionnaire, HAQ) and health- related quality of life measures (SF-36) were prospectively collected since 2001. Comparison between those with and without orthopaedic surgical procedures (groups I and II respectively) at entry to the registry till 2013 or death was done. Risk factors for surgery at study entry were determined using logistic regression (STATA SE 10), adjusted for age and disease duration.ResultsThe study comprised of 1049 patients, predominately Chinese (77.9%); 190 patients (18.1%) had surgery (synovectomy 6.4%, arthroplasty 17.5%, arthodesis 1.1%). The mean age of groups I and II were similar (49.2 vs 48.2 years, p=0.35), mean duration from onset of RA to 1st joint surgery was 136.2 months. Group I had significantly longer symptoms before seeking rheumatologists (mean 63.5 vs 32.0 months, p