AB0365 Prevalence and Factors Associated with Depression and Anxiety in Patients with Rheumatoid Arthritis Using Data from a Large Japanese Cohort Database in 2013 (Ninja 2013 Database)
BackgroundDepression and anxiety have been recognized as prevalent in patients with rheumatoid arthritis (RA), but the exact prevalence among Japanese RA patients is unclear.ObjectivesWe aimed to analyze the prevalence and factors associated with depression and anxiety in RA patients using data from...
Gespeichert in:
Veröffentlicht in: | Annals of the rheumatic diseases 2015-06, Vol.74 (Suppl 2), p.1015-1015 |
---|---|
Hauptverfasser: | , , , , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | BackgroundDepression and anxiety have been recognized as prevalent in patients with rheumatoid arthritis (RA), but the exact prevalence among Japanese RA patients is unclear.ObjectivesWe aimed to analyze the prevalence and factors associated with depression and anxiety in RA patients using data from a large Japanese cohort database.MethodsThe 7,479 patients analyzed in this study were enrolled in the National Database of Rheumatic Diseases by iR-net in Japan (NinJa database), one of the largest clinical databases for RA patients in Japan during the fiscal year of 2013 with results from the Hospital Anxiety and Depression Scale (HADS). For depression, RA patients were divided into two groups: a depression group (DG) with score ≥11, suggesting probable depression; and non-DG, with score ≤10. Differences in clinical data were analyzed between groups. For anxiety, an anxiety group (AG) with score ≥11 and non-AG with score ≤10 were also analyzed.ResultsThe frequency of DG was 9.2%, which is the same as the frequency in the previous year (9.3%) and that of AG 7.0%, which was lower than that in the previous year (8.6%). Mean age was significantly higher in DG and AG than in non-DG and non-AG. In addition, DG and AG showed significantly longer duration of disease, modified Health Assessment Questionnaire (mHAQ) score and higher disease activity score 28 using C-reactive protein (DAS28-CRP), than in non-DG. Furthermore, DG showed a higher stage of progression of joint damage and a higher class of functional impairment. Univariate analyses identified mHAQ and class of functional impairment as factors independently associated with DG and AG. Multivariate logistic regression analyses identified mHAQ as factors independently associated with DG (p |
---|---|
ISSN: | 0003-4967 1468-2060 |
DOI: | 10.1136/annrheumdis-2015-eular.4265 |