AB0347 Effects of Physical Activity and Anti-TNF-Alpha Disease Control on Lipid Profile of Rheumatoid Arthritis Patients

BackgroundRheumatoid arthritis (RA) is a chronic inflammatory disease associated with reduced life expectancy mainly due to an increased incidence of cardiovascular diseases (CVD). Chronic inflammation seems to play a key role in accelerated rate of CVD in RA. Exercise is commonly used to reduce metabolic CV risk factors, but as disease activity influences both inflammatory status and movement capability of RA patients, several studies lack to understand the real outcome of biological treatment on lipid profile, and conflicting results have been found for anti-TNF agents.ObjectivesTo investigate the effect of a structured rehabilitation program on lipid profile of RA patients with low-disease activity/remission during anti-TNF treatment.MethodsThis study included RA patients, referred to our outpatient clinics from June to December 2013, achieving the DAS28