SAT0268 Gender Differences in the Response to Anti-TNF Treatment in Axial SPA

BackgroundAxial-Spondyloarthritis (ax-SpA) often shows a different clinical phenotype in females than in males. Radiographic changes are usually worse in males than in females while women report more functional limitations (1).ObjectivesTo investigate whether changes in spinal mobility under anti-TNF therapy, differ by gender.MethodsAssessment of the Bath status was performed at baseline and after 3, 6, 12 and 24 months respectively in ax-SpA patients (n=77) enrolled at the beginning of their first biologic treatment with anti-TNF. Non-parametric statistics were used. Significance represented as p