Resistance status of aedes sp strain from high land in central java, indonesia, as an indicator of increasing vector's capacity of dengue hemorrhagic fever

Context: The increased cases of dengue hemorrhagic fever (DHF) have been reported in the highland of Wonosobo District. Vector-control program are used for prevention and control of dengue cases. Vector's profile toward insecticide efficacy is important which need to be elucidated. Aims: The aim of this study was to describe the resistance status of the vector against malathion insecticide. Settings and Design: A cross-sectional survey was done in the highland area, Wonosobo sub-district, Indonesia. Methods and Material: The study included a sample of 37 villages, which were located at Wonosobo sub-district. At every village, we observed 15 houses. The observed variables were mosquito bionomic, and their resistance status was based on the biochemical and molecular parameters. To detect resistance status, we used ELISA equipment. Statistical analysis used: Data were collected by entomology students and were analyzed using descriptive statistics. Results: The study results showed that the population of Aedes sp in the Wonosobo District was higher than the standard control of dengue program. Vector indexes were HI (14.75%), CI (6.8%), BI (15.6%), and OI (11.3%). We identified that vectors have already developed resistant to organophosphate insecticide, as many as 50% out of the total sample tested. Conclusions: This finding indicated that Aedes sp strain in the Wonosobo District highland has competence to be dengue vectors. Therefore, it is important to use another type of insecticide such as pyrethroid.