Ultrasonic and Grinding Aptitudes of One‐Pot Synthesis of 5‐(4‐Chlorophenyl)‐7‐(3,4‐Dimethyl Phenyl)‐2‐oxo‐2H‐PyranoPyridine Derivatives as Antibacterial Agents

A simple facile “one‐pot” synthesis of 5‐(4‐chlorophenyl)‐7‐(3,4‐dimethyl phenyl)‐2‐oxo‐2H‐pyrano[2,3‐b]pyridine derivatives via three‐component reaction of chalcone, ethyl‐2‐substituted acetate, and ammonium acetate under ultrasonic irradiation and grinding tools. The newly synthesized compounds we...

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Veröffentlicht in:Journal of heterocyclic chemistry 2017-05, Vol.54 (3), p.2003-2011
Hauptverfasser: Rizk, Sameh A, Maher A El‐Hashash, Azza A El‐Badawy
Format: Artikel
Sprache:eng
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Zusammenfassung:A simple facile “one‐pot” synthesis of 5‐(4‐chlorophenyl)‐7‐(3,4‐dimethyl phenyl)‐2‐oxo‐2H‐pyrano[2,3‐b]pyridine derivatives via three‐component reaction of chalcone, ethyl‐2‐substituted acetate, and ammonium acetate under ultrasonic irradiation and grinding tools. The newly synthesized compounds were evaluated for their antibacterial activity against ATCC 25923, ATCC 10987, ATCC 274, and SM514. All the synthesized compounds have been characterized on the basis of their elemental analyses and spectral data.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.2797