PROCEDURAL SUCCESS RATE OF CARDIAC RESYNCHRONIZATION THERAPY AND DEFIBRILLATOR IMPLANTATION IN HEART FAILURE PATIENTS

ABSTRACT Objective: To determine the success rate of cardiac resynchronization therapy and defibrillator implantation in heart failure patients. INTRODUCTION Heart failure (HF) has become a major disease burden in last two decades due to aging population, growing incidence of diabetes, hypertension, obesity, improved survival after Myocardial Iinfarction (MI) and success in preventing sudden cardiac death1,2. Medical therapies, such as angiotensin converting enzyme (ACE) inhibitors, beta blockers, and spironolactone have markedly improved both symptom control and overall survival in patients with heart failure. Success of the CRT-D was ascertained on the basis of 3 criteria: * One class Improvement in NYHA class of heart failure accessed clinically on 6th post CRT-D implantation day. * Conversion of LBBB to normal QRS complexes determined on ECG Immediately after CRT-D implantation. * 5% or more improvement in EF measured by echocardiography on 6th post CRT-D implantation day. Prevention of heart failure: A scientific statement from American Heart Association Councils on Epidemiology and Prevention, Clinical Cardiology, Cardiovascular Nursing, and High Blood Pressure Research; Quality of Care and Outcomes Research Interdisciplinary Working Group. Bristow MR, Saxon LA, Boehmer J. Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. Williams LK, Ellery S, Patel K. Short-term hemodynamic effects of cardiac resynchronization therapy in patients with heart failure, a narrow QRS duration, and no dyssynchrony. ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise...