Function of Cryopreserved Mesenchymal Stromal Cells With and Without Interferon-[gamma] Prelicensing is Context Dependent

Function of Cryopreserved Mesenchymal Stromal Cells With and Without Interferon-[gamma] Prelicensing is Context Dependent

Tailoring MSCs to fit the disease. Fresh, cryopreserved and, prelicensed cryopreserved MSC are all being explored to treat numerous diseases, but all are not suitable to treat all conditions. injury. "*" denotes preferred therapeutic strategy when both fresh MSC and cryo-MSC have shown uti...

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Veröffentlicht in:Stem cells (Dayton, Ohio) Ohio), 2017-05, Vol.35 (5), p.1437
Hauptverfasser: Burand, Anthony J, Gramlich, Oliver W, Brown, Alex J, Ankrum, James A
Format: Artikel
Sprache:eng
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Abbreviations
Biocompatibility
Biomedical materials
Cryopreservation
Graft-versus-host reaction
Interferon
Ischemia
Mesenchymal stem cells
Mesenchyme
Osteogenesis
Osteogenesis imperfecta
Reperfusion
Stromal cells
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Zusammenfassung:Tailoring MSCs to fit the disease. Fresh, cryopreserved and, prelicensed cryopreserved MSC are all being explored to treat numerous diseases, but all are not suitable to treat all conditions. injury. "*" denotes preferred therapeutic strategy when both fresh MSC and cryo-MSC have shown utility in treating the disease but one is more efficacious or logistically suitable. Abbreviations: CLI, critical limb ischemia; GvHD. graft versus host disease; I/R, ischemia reperfusion (I/R); OI, osteogenesis imperfecta.
ISSN:1066-5099
1549-4918
DOI:10.1002/stem.2528