Hemisynthesis and Spectroscopic Characterization of Three New Chalcone Derivatives from Dorstenia barteri

The hemisynthesis of three new chalcones, namely kenzanol, kelianol A, and kelianol B, from Dorstenia barteri (Moraceae) is described here for the first time. The synthetic pathways employed in this work involved the pyrolysis and catalytic hydrogenation of readily available and starting materials, 4-hydroxylonchocarpin and isobavachalcone, two major constituents of the herbaceous plant D. barteri . The structural elucidation of all the compounds was done by mass spectrometry, IR, UV, 1D and 2D NMR analysis, and also by comparison with previous reports.