Cellulose-SO3H catalyzed synthesis of bis(α-aminophosphonates) and their antioxidant activity

A simple and efficient synthesis of bis(α-aminophosphonates) has been developed by the reaction of aromatic aldehydes, 1,4-phenylenediamine and diethylphosphite in the presence of cellulose-SO 3H as catalyst under neat conditions at room temperature for 10-30 minutes. The synthesized compounds were screened for their antioxidant activity against DPPH, NO and H 2O 2 scavenging methods. All the compounds exhibited good to moderate activity.