Pyrimidines as Surrogates for 1,3‐Dicarbonyl Compounds in peri Annulation of Perimidines en Route to 1,3‐Diazapyrenes

A highly efficient protocol for acid‐mediated peri annulation of perimidines with pyrimidines has been developed. Pyrimidines, used as surrogates for 1,3‐dicarbonyl compounds, furnish benzo[gh]perimidines, which includes hardly available analogues, non‐substituted, or mono‐substituted at C‐6, C‐8. Limitations of reactions that use 5‐bromopyrimidines are investigated. A highly efficient protocol for acid‐mediated peri annulation of perimidines with pyrimidines has been developed. Pyrimidines, used as surrogates for 1,3‐dicarbonyl compounds, furnish benzo[gh]perimidines, which includes hardly available analogues, non‐substituted, or mono‐substituted at C‐6, C‐8.