ChemInform Abstract: 1-Bromo-2-trifluoroacetylcyclobutenes as Novel Building Blocks for the Construction of Trifluoromethyl Substituted Heterocycles. Part 1. Synthesis of 5-(Trifluoromethyl)-2(5H)-furanones Condensed with Substituted Cyclobutenes

ChemInform Abstract: 1-Bromo-2-trifluoroacetylcyclobutenes as Novel Building Blocks for the Construction of Trifluoromethyl Substituted Heterocycles. Part 1. Synthesis of 5-(Trifluoromethyl)-2(5H)-furanones Condensed with Substituted Cyclobutenes

The lithiation of bromides (II) followed by carboxylation leads to acids (IV), which are readily converted into the desired lactones (V) by the action of trifluoroacetic anhydride.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:ChemInform 2010-10, Vol.41 (42), p.no-no
Hauptverfasser: Koldobskii, Andrey B., Tsvetkov, Nikolay P., Solodova, Ekaterina V., Kalinin, Valery N.
Format: Artikel
Sprache:eng
Schlagworte:
furan derivatives
ring closure reactions
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The lithiation of bromides (II) followed by carboxylation leads to acids (IV), which are readily converted into the desired lactones (V) by the action of trifluoroacetic anhydride.
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201042091