Limonoids from the Seeds of Chisocheton macrophyllus
A new limonoid compound, dysobinol ( 1 ), along with three known limonoid compounds, 7α-hydroxyneotricilenone ( 2 ), dysobinin ( 3 ), and nimonol ( 4 ), was isolated from the seeds of Chisocheton macrophyllus (Meliaceae). Their structures were established by spectroscopic techniques such as UV, IR,...
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| Veröffentlicht in: | Chemistry of natural compounds 2017, Vol.53 (1), p.83-87 |
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| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | A new limonoid compound, dysobinol (
1
), along with three known limonoid compounds, 7α-hydroxyneotricilenone (
2
), dysobinin (
3
), and nimonol (
4
), was isolated from the seeds of Chisocheton macrophyllus (Meliaceae). Their structures were established by spectroscopic techniques such as UV, IR, MS, 1D, and 2D NMR. Compounds
1–4
showed cytotoxic activity against P-388 murine leukemia cells with IC
50
values of 49.7, 79.4, 19.5, and 64.5 μg/mL, respectively. |
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| ISSN: | 0009-3130 1573-8388 |
| DOI: | 10.1007/s10600-017-1916-4 |