Synthesis of flower-like cuo hierarchical nanostructures as an electrochemical platform for glucose sensing

Flower-like CuO hierarchical nanostructures were synthesized on copper foil substrate through a simple wet chemical route in alkaline media at room temperature. SEM images collected at different reaction times revealed the transformation of initially formed Cu(OH) 2 nanowires to flower-like CuO nanostructures. The hierarchical structure of the as-prepared CuO showed high electrocatalytic activity towards the oxidation of glucose making it a promising electrode material for the development of non-enzymatic glucose sensor. The amperometric sensor exhibited a wide linear response to glucose ranging from 4.5 × 10 −5 to 1.3 × 10 −3 mol L −1 ( R 2 = 0.99317) at fixed potential of 0.3 V. The detection limit was 6.9 × 10 −6 mol L −1 (LOD = 3 σ / s ) with a sensitivity of 1.71 μA μmol −1 cm −2 . Moreover, the developed sensor offers a fast amperometric response, good selectivity and stability.