Associates of thioalkyl derivatives of 2-arylaminopyrimidine with hydroxyapatite-based nanocomposites
Co-precipitation and ultrasonic treatment methods have been used for the in situ formation of the composites of hydroxyapatite (HA) covered with nanoparticles of magnetite as well as compositions of magnetite, gold and silver. The thioalkyl-substituted derivatives of 2-arylaminopyrimidine, structura...
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Veröffentlicht in: | Russian journal of general chemistry 2016-08, Vol.86 (8), p.1886-1895 |
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container_issue | 8 |
container_start_page | 1886 |
container_title | Russian journal of general chemistry |
container_volume | 86 |
creator | Eryomin, A. N. Pietkievich, A. V. Abakshonok, A. V. Siniutsich, Yu. V. Ignatovich, Zh. V. Agabekov, V. E. Al-Muhanna, M. K. |
description | Co-precipitation and ultrasonic treatment methods have been used for the in situ formation of the composites of hydroxyapatite (HA) covered with nanoparticles of magnetite as well as compositions of magnetite, gold and silver. The thioalkyl-substituted derivatives of 2-arylaminopyrimidine, structural analogs of antitumor drug Imatinib containing one or two SH groups and capable to chemisorption on hydroxyapatite and its nanocomposites, have been synthesized. Two-component Fe
3
O
4
(HA) and three-component Fe
3
O
4
(HA)Au and Fe
3
O
4
(HA)Ag composites have been found the most promising as nanocarriers of bioactive compounds. |
doi_str_mv | 10.1134/S1070363216080181 |
format | Article |
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3
O
4
(HA) and three-component Fe
3
O
4
(HA)Au and Fe
3
O
4
(HA)Ag composites have been found the most promising as nanocarriers of bioactive compounds.</description><identifier>ISSN: 1070-3632</identifier><identifier>EISSN: 1608-3350</identifier><identifier>DOI: 10.1134/S1070363216080181</identifier><language>eng</language><publisher>Moscow: Pleiades Publishing</publisher><subject>Chemisorption ; Chemistry ; Chemistry and Materials Science ; Chemistry/Food Science ; Hydroxyapatite ; Iron oxides ; Magnetite ; Nanocomposites ; Particulate composites ; Silver ; Ultrasonic processing</subject><ispartof>Russian journal of general chemistry, 2016-08, Vol.86 (8), p.1886-1895</ispartof><rights>Pleiades Publishing, Ltd. 2016</rights><rights>Copyright Springer Science & Business Media 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c316t-bde341f8894a8995c4abc93bf2ff8bfa07bae576af5bca38a89298bdf77d96113</citedby><cites>FETCH-LOGICAL-c316t-bde341f8894a8995c4abc93bf2ff8bfa07bae576af5bca38a89298bdf77d96113</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1134/S1070363216080181$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1134/S1070363216080181$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids></links><search><creatorcontrib>Eryomin, A. N.</creatorcontrib><creatorcontrib>Pietkievich, A. V.</creatorcontrib><creatorcontrib>Abakshonok, A. V.</creatorcontrib><creatorcontrib>Siniutsich, Yu. V.</creatorcontrib><creatorcontrib>Ignatovich, Zh. V.</creatorcontrib><creatorcontrib>Agabekov, V. E.</creatorcontrib><creatorcontrib>Al-Muhanna, M. K.</creatorcontrib><title>Associates of thioalkyl derivatives of 2-arylaminopyrimidine with hydroxyapatite-based nanocomposites</title><title>Russian journal of general chemistry</title><addtitle>Russ J Gen Chem</addtitle><description>Co-precipitation and ultrasonic treatment methods have been used for the in situ formation of the composites of hydroxyapatite (HA) covered with nanoparticles of magnetite as well as compositions of magnetite, gold and silver. The thioalkyl-substituted derivatives of 2-arylaminopyrimidine, structural analogs of antitumor drug Imatinib containing one or two SH groups and capable to chemisorption on hydroxyapatite and its nanocomposites, have been synthesized. Two-component Fe
3
O
4
(HA) and three-component Fe
3
O
4
(HA)Au and Fe
3
O
4
(HA)Ag composites have been found the most promising as nanocarriers of bioactive compounds.</description><subject>Chemisorption</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Chemistry/Food Science</subject><subject>Hydroxyapatite</subject><subject>Iron oxides</subject><subject>Magnetite</subject><subject>Nanocomposites</subject><subject>Particulate composites</subject><subject>Silver</subject><subject>Ultrasonic processing</subject><issn>1070-3632</issn><issn>1608-3350</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNp1kMtOwzAQRS0EEqXwAewisQ544jzsZVXxkiqxANbR2LGpSxoHOy3k73EVFkiI1YzmnjujuYRcAr0GYPnNM9CKspJlUFJOgcMRmR3alLGCHsc-yulBPyVnIWwoBUrLbEb0IgSnLA46JM4kw9o6bN_HNmm0t3sc7H4SshT92OLWdq4fvd3axnY6-bTDOlmPjXdfI_aRHnQqMegm6bBzym17F-IsnJMTg23QFz91Tl7vbl-WD-nq6f5xuVilikE5pLLRLAfDuciRC1GoHKUSTJrMGC4N0kqiLqoSTSEVMh6hTHDZmKpqRBlzmJOraW_v3cdOh6HeuJ3v4skaOKe8BJHxSMFEKe9C8NrUffwo_lcDrQ9p1n_SjJ5s8oTIdm_a_9r8r-kbdLV5dw</recordid><startdate>20160801</startdate><enddate>20160801</enddate><creator>Eryomin, A. N.</creator><creator>Pietkievich, A. V.</creator><creator>Abakshonok, A. V.</creator><creator>Siniutsich, Yu. V.</creator><creator>Ignatovich, Zh. V.</creator><creator>Agabekov, V. E.</creator><creator>Al-Muhanna, M. K.</creator><general>Pleiades Publishing</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20160801</creationdate><title>Associates of thioalkyl derivatives of 2-arylaminopyrimidine with hydroxyapatite-based nanocomposites</title><author>Eryomin, A. N. ; Pietkievich, A. V. ; Abakshonok, A. V. ; Siniutsich, Yu. V. ; Ignatovich, Zh. V. ; Agabekov, V. E. ; Al-Muhanna, M. K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c316t-bde341f8894a8995c4abc93bf2ff8bfa07bae576af5bca38a89298bdf77d96113</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Chemisorption</topic><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Chemistry/Food Science</topic><topic>Hydroxyapatite</topic><topic>Iron oxides</topic><topic>Magnetite</topic><topic>Nanocomposites</topic><topic>Particulate composites</topic><topic>Silver</topic><topic>Ultrasonic processing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Eryomin, A. N.</creatorcontrib><creatorcontrib>Pietkievich, A. V.</creatorcontrib><creatorcontrib>Abakshonok, A. V.</creatorcontrib><creatorcontrib>Siniutsich, Yu. V.</creatorcontrib><creatorcontrib>Ignatovich, Zh. V.</creatorcontrib><creatorcontrib>Agabekov, V. E.</creatorcontrib><creatorcontrib>Al-Muhanna, M. K.</creatorcontrib><collection>CrossRef</collection><jtitle>Russian journal of general chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Eryomin, A. N.</au><au>Pietkievich, A. V.</au><au>Abakshonok, A. V.</au><au>Siniutsich, Yu. V.</au><au>Ignatovich, Zh. V.</au><au>Agabekov, V. E.</au><au>Al-Muhanna, M. K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Associates of thioalkyl derivatives of 2-arylaminopyrimidine with hydroxyapatite-based nanocomposites</atitle><jtitle>Russian journal of general chemistry</jtitle><stitle>Russ J Gen Chem</stitle><date>2016-08-01</date><risdate>2016</risdate><volume>86</volume><issue>8</issue><spage>1886</spage><epage>1895</epage><pages>1886-1895</pages><issn>1070-3632</issn><eissn>1608-3350</eissn><abstract>Co-precipitation and ultrasonic treatment methods have been used for the in situ formation of the composites of hydroxyapatite (HA) covered with nanoparticles of magnetite as well as compositions of magnetite, gold and silver. The thioalkyl-substituted derivatives of 2-arylaminopyrimidine, structural analogs of antitumor drug Imatinib containing one or two SH groups and capable to chemisorption on hydroxyapatite and its nanocomposites, have been synthesized. Two-component Fe
3
O
4
(HA) and three-component Fe
3
O
4
(HA)Au and Fe
3
O
4
(HA)Ag composites have been found the most promising as nanocarriers of bioactive compounds.</abstract><cop>Moscow</cop><pub>Pleiades Publishing</pub><doi>10.1134/S1070363216080181</doi><tpages>10</tpages></addata></record> |
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source | Springer Nature - Complete Springer Journals |
subjects | Chemisorption Chemistry Chemistry and Materials Science Chemistry/Food Science Hydroxyapatite Iron oxides Magnetite Nanocomposites Particulate composites Silver Ultrasonic processing |
title | Associates of thioalkyl derivatives of 2-arylaminopyrimidine with hydroxyapatite-based nanocomposites |
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