Synthesis and Preliminary Cancer Cell Line Results for the Product of Organotin Dihalides and Alpha-Cyano-4-Hydroxycinnamic Acid

High polymer poly(ester ethers) are rapidly synthesized in good yield employing the interfacial polycondensation reaction system. Infrared spectroscopy shows the formation of new bands derived from the Sn–O and Sn–O(CO) linkages. It also shows that the products exist as alternating Sn–O and Sn–O(CO)...

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Veröffentlicht in:Journal of inorganic and organometallic polymers and materials 2016-11, Vol.26 (6), p.1351-1361
Hauptverfasser: Carraher, Charles E., Roner, Michael R., Chrichton, Ryan, Moric-Johnson, Alisa, Miller, Lindsey, Black, Kendra, Russell, Floyd
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Sprache:eng
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Zusammenfassung:High polymer poly(ester ethers) are rapidly synthesized in good yield employing the interfacial polycondensation reaction system. Infrared spectroscopy shows the formation of new bands derived from the Sn–O and Sn–O(CO) linkages. It also shows that the products exist as alternating Sn–O and Sn–O(CO) linkages. MALDI MS shows formation of ion fragment clusters several units in length. The products show reasonable inhibition of a variety of cancer cell lines including two pancreatic cancer cell lines.
ISSN:1574-1443
1574-1451
DOI:10.1007/s10904-016-0363-1