Synthesis and biological activity of quaternary phosphonium salts based on 3-hydroxypyridine and 4-deoxypyridoxine

Synthesis and biological activity of quaternary phosphonium salts based on 3-hydroxypyridine and 4-deoxypyridoxine

Methods for the synthesis of quaternary phosphonium salts based on 3-hydroxypyridine and 4-deoxypyridoxine were developed. Some of obtained compounds possess high antibacterial and antitumor activity in vitro .

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Veröffentlicht in:Russian chemical bulletin 2016-02, Vol.65 (2), p.537-545
Hauptverfasser: Shtyrlin, N. V., Vafina, R. M., Pugachev, M. V., Khaziev, R. M., Nikitina, E. V., Zeldi, M. I., Iksanova, A. G., Shtyrlin, Yu. G.
Format: Artikel
Sprache:eng
Schlagworte:
Antibacterial materials
Anticancer properties
Biological activity
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Full Articles
In vitro testing
Inorganic Chemistry
Organic Chemistry
Synthesis
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Zusammenfassung:Methods for the synthesis of quaternary phosphonium salts based on 3-hydroxypyridine and 4-deoxypyridoxine were developed. Some of obtained compounds possess high antibacterial and antitumor activity in vitro .
ISSN:1066-5285
1573-9171
DOI:10.1007/s11172-016-1334-y