Synthesis of new derivatives of 5-(3,4-dihydro-2Н-pyrrol-5-yl)-pyrimidine

By one-stage condensation of 6-(arylamino)pyrimidine-2,4(1 Н ,3 Н )-diones with pyrrolidin-2-one new potential antiviral compounds were obtained, analogs of pyrrolinylpyrimidine containing structural fragments of known drugs AZT and HEPT used in treating HIV-infections.

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Bibliographische Detailangaben
Veröffentlicht in:	Russian journal of organic chemistry 2016-11, Vol.52 (11), p.1646-1653
Hauptverfasser:	Gasparyan, S. P., Alexanyan, M. V., Arutyunyan, G. K., Kocharov, S. L., Martirosyan, A. H., Tamazyan, R. A., Ayvazyan, A. G., Panosyan, H. A., Danagulyan, G. G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Chemistry and Materials Science Diketones Fragments Organic Chemistry Zidovudine
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	By one-stage condensation of 6-(arylamino)pyrimidine-2,4(1 Н ,3 Н )-diones with pyrrolidin-2-one new potential antiviral compounds were obtained, analogs of pyrrolinylpyrimidine containing structural fragments of known drugs AZT and HEPT used in treating HIV-infections.
ISSN:	1070-4280 1608-3393
DOI:	10.1134/S1070428016110166