Potential synthetic adaptogens 1. Synthesis and studies of new N-[(adamantan-1-yl)methyl]aniline derivatives based on adamantane-1-carbaldehyde

A number of new N -[(adamantan-1-yl)methyl]aniline derivatives, which can be considered as conformationally labile analogues of synthetic adaptogen Bromantan, were obtained by the reductive amination reaction of adamantane-1-carbaldehyde with aromatic amines. The influence of the reaction conditions...

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Veröffentlicht in:Russian chemical bulletin 2016-05, Vol.65 (5), p.1336-1340
Hauptverfasser: Voloboev, S. N., Andreev, A. V., Mkrtchyan, A. S., Navrotskii, M. B., Novakov, I. A., Orlinson, B. S., Son, V. V.
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container_issue 5
container_start_page 1336
container_title Russian chemical bulletin
container_volume 65
creator Voloboev, S. N.
Andreev, A. V.
Mkrtchyan, A. S.
Navrotskii, M. B.
Novakov, I. A.
Orlinson, B. S.
Son, V. V.
description A number of new N -[(adamantan-1-yl)methyl]aniline derivatives, which can be considered as conformationally labile analogues of synthetic adaptogen Bromantan, were obtained by the reductive amination reaction of adamantane-1-carbaldehyde with aromatic amines. The influence of the reaction conditions of reductive amination on the yield and composition of its products was studied.
doi_str_mv 10.1007/s11172-016-1458-0
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subjects Adaptogens
Amines
Aniline
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Derivatives
Full Articles
Inorganic Chemistry
Organic Chemistry
title Potential synthetic adaptogens 1. Synthesis and studies of new N-[(adamantan-1-yl)methyl]aniline derivatives based on adamantane-1-carbaldehyde
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