Potential synthetic adaptogens 1. Synthesis and studies of new N-[(adamantan-1-yl)methyl]aniline derivatives based on adamantane-1-carbaldehyde
A number of new N -[(adamantan-1-yl)methyl]aniline derivatives, which can be considered as conformationally labile analogues of synthetic adaptogen Bromantan, were obtained by the reductive amination reaction of adamantane-1-carbaldehyde with aromatic amines. The influence of the reaction conditions...
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Veröffentlicht in: | Russian chemical bulletin 2016-05, Vol.65 (5), p.1336-1340 |
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container_title | Russian chemical bulletin |
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creator | Voloboev, S. N. Andreev, A. V. Mkrtchyan, A. S. Navrotskii, M. B. Novakov, I. A. Orlinson, B. S. Son, V. V. |
description | A number of new
N
-[(adamantan-1-yl)methyl]aniline derivatives, which can be considered as conformationally labile analogues of synthetic adaptogen Bromantan, were obtained by the reductive amination reaction of adamantane-1-carbaldehyde with aromatic amines. The influence of the reaction conditions of reductive amination on the yield and composition of its products was studied. |
doi_str_mv | 10.1007/s11172-016-1458-0 |
format | Article |
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-[(adamantan-1-yl)methyl]aniline derivatives, which can be considered as conformationally labile analogues of synthetic adaptogen Bromantan, were obtained by the reductive amination reaction of adamantane-1-carbaldehyde with aromatic amines. The influence of the reaction conditions of reductive amination on the yield and composition of its products was studied.</description><subject>Adaptogens</subject><subject>Amines</subject><subject>Aniline</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Chemistry/Food Science</subject><subject>Derivatives</subject><subject>Full Articles</subject><subject>Inorganic Chemistry</subject><subject>Organic Chemistry</subject><issn>1066-5285</issn><issn>1573-9171</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNp1kMtKxDAUhosoeH0AdwE3usiYpG2SLkW8gaigrkRC0pw6kU46JhmlT-Erm3FE3Lg6h8P3_Qf-otinZEIJEceRUioYJpRjWtUSk7Vii9aixA0VdD3vhHNcM1lvFtsxvhJCmJRyq_i8GxL45HSP4ujTFJJrkbZ6noYX8BHRCbr_vkcXkfYWxbSwDiIaOuThA93gp8OMz7RP2mOKx_5oBmk69s_au955QBaCe9fJvWfJ6AgWDR79KpCdVgejewvT0cJusdHpPsLez9wpHs_PHk4v8fXtxdXpyTVuS8oTNoZbw4RhXQumIV0lm8rI2jRMWC46S6QWtrHGdh3hTVXzyvBSE16CrOq25uVOcbDKnYfhbQExqddhEXx-qaiURDSsZFWm6IpqwxBjgE7Ng5vpMCpK1LJ3tepd5d7VsndFssNWTsysf4HwJ_lf6QvLB4fR</recordid><startdate>20160501</startdate><enddate>20160501</enddate><creator>Voloboev, S. N.</creator><creator>Andreev, A. V.</creator><creator>Mkrtchyan, A. S.</creator><creator>Navrotskii, M. B.</creator><creator>Novakov, I. A.</creator><creator>Orlinson, B. S.</creator><creator>Son, V. V.</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20160501</creationdate><title>Potential synthetic adaptogens 1. Synthesis and studies of new N-[(adamantan-1-yl)methyl]aniline derivatives based on adamantane-1-carbaldehyde</title><author>Voloboev, S. N. ; Andreev, A. V. ; Mkrtchyan, A. S. ; Navrotskii, M. B. ; Novakov, I. A. ; Orlinson, B. S. ; Son, V. V.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c316t-bb6db27b2fceb90f4894b85b927d67fd08a7d9dbdff0694564b63a063e845c563</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adaptogens</topic><topic>Amines</topic><topic>Aniline</topic><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Chemistry/Food Science</topic><topic>Derivatives</topic><topic>Full Articles</topic><topic>Inorganic Chemistry</topic><topic>Organic Chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Voloboev, S. N.</creatorcontrib><creatorcontrib>Andreev, A. V.</creatorcontrib><creatorcontrib>Mkrtchyan, A. S.</creatorcontrib><creatorcontrib>Navrotskii, M. B.</creatorcontrib><creatorcontrib>Novakov, I. A.</creatorcontrib><creatorcontrib>Orlinson, B. S.</creatorcontrib><creatorcontrib>Son, V. V.</creatorcontrib><collection>CrossRef</collection><jtitle>Russian chemical bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Voloboev, S. N.</au><au>Andreev, A. V.</au><au>Mkrtchyan, A. S.</au><au>Navrotskii, M. B.</au><au>Novakov, I. A.</au><au>Orlinson, B. S.</au><au>Son, V. V.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Potential synthetic adaptogens 1. Synthesis and studies of new N-[(adamantan-1-yl)methyl]aniline derivatives based on adamantane-1-carbaldehyde</atitle><jtitle>Russian chemical bulletin</jtitle><stitle>Russ Chem Bull</stitle><date>2016-05-01</date><risdate>2016</risdate><volume>65</volume><issue>5</issue><spage>1336</spage><epage>1340</epage><pages>1336-1340</pages><issn>1066-5285</issn><eissn>1573-9171</eissn><abstract>A number of new
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-[(adamantan-1-yl)methyl]aniline derivatives, which can be considered as conformationally labile analogues of synthetic adaptogen Bromantan, were obtained by the reductive amination reaction of adamantane-1-carbaldehyde with aromatic amines. The influence of the reaction conditions of reductive amination on the yield and composition of its products was studied.</abstract><cop>New York</cop><pub>Springer US</pub><doi>10.1007/s11172-016-1458-0</doi><tpages>5</tpages></addata></record> |
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subjects | Adaptogens Amines Aniline Chemistry Chemistry and Materials Science Chemistry/Food Science Derivatives Full Articles Inorganic Chemistry Organic Chemistry |
title | Potential synthetic adaptogens 1. Synthesis and studies of new N-[(adamantan-1-yl)methyl]aniline derivatives based on adamantane-1-carbaldehyde |
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