Synthesis of (5Z,5´Z)-3,3´-(alkane-α,ω-diyl)bis[5-(2-pyridylmethylidene)-2-methylthio-3,5-dihydro-4H-imidazol-4-ones] and their coordination compounds with copper(ii)

A synthesis of copper( ii ) coordination compounds based on the new tetradentate organic ligands from the series of (5 Z ,5´ Z )-3,3´-(alkane-α,ω-diyl)bis[5-(2-pyridylmethylidene)-2-thio-3,5-dihydro-4 H -imidazol-4-ones] was suggested. Biological activity of the copper( ii ) coordination compounds w...

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Veröffentlicht in:Russian chemical bulletin 2016-05, Vol.65 (5), p.1254-1259
Hauptverfasser: Tishchenko, K. I., Beloglazkina, E. K., Proskurnin, M. A., Mazhuga, A. G., Muratova, M. E., Skvortsov, D. A., Zyk, N. V.
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Sprache:eng
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Zusammenfassung:A synthesis of copper( ii ) coordination compounds based on the new tetradentate organic ligands from the series of (5 Z ,5´ Z )-3,3´-(alkane-α,ω-diyl)bis[5-(2-pyridylmethylidene)-2-thio-3,5-dihydro-4 H -imidazol-4-ones] was suggested. Biological activity of the copper( ii ) coordination compounds was studied, their ability to inhibit telomerase activity was shown.
ISSN:1066-5285
1573-9171
DOI:10.1007/s11172-016-1444-6