The Grandberg reaction in the synthesis of biologically active compounds

The review is focused on the Grandberg synthesis, namely, the synthesis of tryptamines from arylhydrazines and γ-halocarbonyl compounds, as an exceptionally useful and efficient methodology to access biologically active indole heterocycles.

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Veröffentlicht in:Russian chemical bulletin 2016-07, Vol.65 (7), p.1709-1715
Hauptverfasser: Przheval’skii, N. M., Laipanov, R. K., Tokmakov, G. P., Nam, N. L.
Format: Artikel
Sprache:eng
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Zusammenfassung:The review is focused on the Grandberg synthesis, namely, the synthesis of tryptamines from arylhydrazines and γ-halocarbonyl compounds, as an exceptionally useful and efficient methodology to access biologically active indole heterocycles.
ISSN:1066-5285
1573-9171
DOI:10.1007/s11172-016-1499-4