PERCUTANEOUS CLOSURE OF PATENT FORAMEN OVALE IS ASSOCIATED WITH LOWER INCIDENCE CRYPTOGENIC STROKES AMONG PATIENTS WITH INHERITED THROMBOPHIALIAS TREATED WITH ANTICOAGULANT OR ANTIAGGREGANT THERAPY

PERCUTANEOUS CLOSURE OF PATENT FORAMEN OVALE IS ASSOCIATED WITH LOWER INCIDENCE CRYPTOGENIC STROKES AMONG PATIENTS WITH INHERITED THROMBOPHIALIAS TREATED WITH ANTICOAGULANT OR ANTIAGGREGANT THERAPY

Higher incidences of cryptogenic strokes are reported in patients with PFO's and inherited thrombophilias (ITs) such as the Prothrombin and Factor V Leiden mutations. Since carriers of IT's are usually maintained on anticoagulant/antiaggregant therapy, the potential benefit of PFO closure...

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Veröffentlicht in:Journal of the American College of Cardiology 2017-03, Vol.69 (11), p.962-962
Hauptverfasser: Buber, Yonatan, Orion, David, Borik, Sharon, Varuri, Ori, Guetta, Victor
Format: Artikel
Sprache:eng
Schlagworte:
Anticoagulants
Cardiology
Cardiovascular
Internal Medicine
Multivariate analysis
Mutation
Stroke
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Zusammenfassung:Higher incidences of cryptogenic strokes are reported in patients with PFO's and inherited thrombophilias (ITs) such as the Prothrombin and Factor V Leiden mutations. Since carriers of IT's are usually maintained on anticoagulant/antiaggregant therapy, the potential benefit of PFO closure in this population is unclear.
ISSN:0735-1097
1558-3597
DOI:10.1016/S0735-1097(17)34351-6