Locational Analysis of Glutathione in Liposomes by Using Small-angle X-ray Scattering

Locational Analysis of Glutathione in Liposomes by Using Small-angle X-ray Scattering

We investigated the effect of the surface charge and volume of the aqueous phase of liposomes on the antioxidant glutathione (GSH) entrapment ratio in liposomes. The entrapment ratio increased by decreasing the molar ratio of the cationic lipid. Furthermore, we investigated in detail the location of...

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Veröffentlicht in:Chemistry letters 2017-02, Vol.46 (2), p.185-187
Hauptverfasser: Sakuragi, Mina, Zushi, Takuya, Seguchi, Risako, Arai, Taishi, Taguchi, Kazuaki, Kusakabe, Katsuki
Format: Artikel
Sprache:eng
Schlagworte:
Antioxidants
Entrapment
Fourier transforms
Glutathione
Lipids
Liposomes
Surface charge
X-ray scattering
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Zusammenfassung:We investigated the effect of the surface charge and volume of the aqueous phase of liposomes on the antioxidant glutathione (GSH) entrapment ratio in liposomes. The entrapment ratio increased by decreasing the molar ratio of the cationic lipid. Furthermore, we investigated in detail the location of the GSH in liposomes with SAXS data using the Fourier transformation method.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.160932