CHEMICAL CHARACTERIZATION OF SPIDER TOXIN, NSTX

CHEMICAL CHARACTERIZATION OF SPIDER TOXIN, NSTX

Toxic principles in the venom of the spider, Nephila maculata, were purified with the reverse phase high performance liquid chromatography, and three kinds of the major toxins (NSTX-1, -2 and -3) were isolated. These principles commonly possessed 2,4-dihydroxyphenylacetyl-asparaginyl-cadaveryl moiet...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biomedical Research 1987/06/01, Vol.8(3), pp.167-173
Hauptverfasser: ARAMAKI, YOSHIO, YASUHARA, TADASHI, HIGASHIJIMA, TSUTOMU, MIWA, AKIKO, NOBUFUMI, KAWAI, NAKAJIMA, TERUMI
Format: Artikel
Sprache:eng
Schlagworte:
Cadaverine
High performance liquid chromatography
Liquid chromatography
Molecular structure
Nephila maculata
Toxins
Venom
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Toxic principles in the venom of the spider, Nephila maculata, were purified with the reverse phase high performance liquid chromatography, and three kinds of the major toxins (NSTX-1, -2 and -3) were isolated. These principles commonly possessed 2,4-dihydroxyphenylacetyl-asparaginyl-cadaveryl moiety in the molecule. The structure of NSTX-3 was concluded to be N-(2,4-dihydroxylphenylacetyl-L-asparaginyl)-N'-(L-arginyl-putreanyl)cadaverine.
ISSN:0388-6107
1880-313X
DOI:10.2220/biomedres.8.167