Fenbendazole. I. Structure-activity relationships

Substitution of alkyl benzimidazol‐2‐ylcarbamates by phenoxy‐ or phenylthio‐groups in the 5‐position results in an increase in anthelmintic activity. The biological spectrum is altered by substitution of the phenyl ring. A sulphonic ester substituent in the 5‐position of the benzimidazole nucleus al...

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Veröffentlicht in:Pesticide Science 1977-10, Vol.8 (5), p.544-549
Hauptverfasser: Loewe, Heinz, Urbanietz, Josef
Format: Artikel
Sprache:eng
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Zusammenfassung:Substitution of alkyl benzimidazol‐2‐ylcarbamates by phenoxy‐ or phenylthio‐groups in the 5‐position results in an increase in anthelmintic activity. The biological spectrum is altered by substitution of the phenyl ring. A sulphonic ester substituent in the 5‐position of the benzimidazole nucleus also increases anthelmintic activity.
ISSN:0031-613X
1526-498X
1096-9063
DOI:10.1002/ps.2780080519