Captopril and Renal Autoregulation

Renal autoregulation of blood flow and glomerular filtration tends to be regarded by both the busy clinician and the struggling student as one of those arcane phenomena that must be important in the grand scheme of biology but whose relevance to clinical medicine is difficult to see. The reports by Curtis 1 and Hricik and their co-workers 2 in this issue of the Journal move our experience with renal autoregulation from the experimental laboratory to the clinic and in so doing provide additional insights into its mechanism. When mean arterial pressure is varied over a wide range, renal blood flow and the . . .