Mechanistic role of Per2 and PPAR-gamma in ethanol mediated hyperpermeability

Mechanistic role of Per2 and PPAR-gamma in ethanol mediated hyperpermeability

To elucidate the role of PPAR-gamma protein in ethanol-induced epithelial barrier dysfunction, we grew Caco-2 cells on cell culture microplates until confluence. TEER reconfirmed the negative effect of ethanol on epithelial barrier function.

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Veröffentlicht in:Alcohol (Fayetteville, N.Y.) N.Y.), 2017-03, Vol.59, p.72-73
Hauptverfasser: Davis, B.T, Shaikh, M, Forsyth, C.B, Keshavarzian, A
Format: Artikel
Sprache:eng
Schlagworte:
Ethanol
Oxidative stress
Permeability
Proteins
Psychiatry
Small intestine
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container_end_page 73
container_issue
container_start_page 72
container_title Alcohol (Fayetteville, N.Y.)
container_volume 59
creator Davis, B.T
Shaikh, M
Forsyth, C.B
Keshavarzian, A
description To elucidate the role of PPAR-gamma protein in ethanol-induced epithelial barrier dysfunction, we grew Caco-2 cells on cell culture microplates until confluence. TEER reconfirmed the negative effect of ethanol on epithelial barrier function.
doi_str_mv 10.1016/j.alcohol.2016.10.023
format Article
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source Elsevier ScienceDirect Journals Complete; ProQuest Central UK/Ireland
subjects Ethanol
Oxidative stress
Permeability
Proteins
Psychiatry
Small intestine
title Mechanistic role of Per2 and PPAR-gamma in ethanol mediated hyperpermeability
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