Allergen Capture by DCs during epicutaneous immunotherapy is Enhanced by Modulating the Dose and the Surface Area of the Patch

Rationale Epicutaneous immunotherapy for the treatment of food allergy is effective and safe in animal models and in humans, as recently shown in a Phase II trial demonstrating the crucial role of the dose.

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Veröffentlicht in:Journal of allergy and clinical immunology 2017-02, Vol.139 (2), p.AB257-AB257
Hauptverfasser: Wavrin, Sophie, Mondoulet, Lucie, Dioszeghy, Vincent, PhD, Puteaux, Emilie, Ligouis, Melanie, Dhelft, Véronique, Plaquet, Camille, Dupont, Christophe M., MD, PhD, Benhamou, Pierre-Henri, Sampson, Hugh A., MD, FAAAAI
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Sprache:eng
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Zusammenfassung:Rationale Epicutaneous immunotherapy for the treatment of food allergy is effective and safe in animal models and in humans, as recently shown in a Phase II trial demonstrating the crucial role of the dose.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2016.12.827