Switch from Intravenous C1-Inhibitor C1-INH(IV) to Subcutaneous C1-Inhibitor [C1 INH(SC)] for Routine Prevention of Hereditary Angioedema (HAE) Attacks: Subgroup Findings from the Compact Trial

Switch from Intravenous C1-Inhibitor C1-INH(IV) to Subcutaneous C1-Inhibitor [C1 INH(SC)] for Routine Prevention of Hereditary Angioedema (HAE) Attacks: Subgroup Findings from the Compact Trial

Rationale The COMPACT (Clinical Studies for Optimal Management of Preventing Angioedema with low-volume subcutaneous C1-Inhibitor Replacement Therapy) trial evaluated the safety and efficacy of a low-volume C1-INH(SC) as routine prevention in patients with HAE.

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Veröffentlicht in:Journal of allergy and clinical immunology 2017-02, Vol.139 (2), p.AB230-AB230
Hauptverfasser: Craig, Timothy J., DO, FAAAAI, Baker, James W., MD, FAAAAI, Lumry, William R., MD, FAAAAI, Farkas, Henriette, Feuersenger, Henrike, Jacobs, Iris
Format: Artikel
Sprache:eng
Schlagworte:
Allergy and Immunology
Prevention
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Zusammenfassung:Rationale The COMPACT (Clinical Studies for Optimal Management of Preventing Angioedema with low-volume subcutaneous C1-Inhibitor Replacement Therapy) trial evaluated the safety and efficacy of a low-volume C1-INH(SC) as routine prevention in patients with HAE.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2016.12.740