Role Of Hormone Signaling In Eosinophilic Esophagitis: 17-Beta Estradiol Attenuation Of IL-13 Induced Barrier Dysfunction In Esophageal Epithelium

Role Of Hormone Signaling In Eosinophilic Esophagitis: 17-Beta Estradiol Attenuation Of IL-13 Induced Barrier Dysfunction In Esophageal Epithelium

The effect of 17-beta estradiol (E2) in esophageal epithelial cell barrier function was examined, aiming to demonstrate E2 promotes cellular and molecular protective effects in EoE relevant assays.

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Bibliographische Detailangaben
Veröffentlicht in:Journal of allergy and clinical immunology 2017-02, Vol.139 (2), p.AB273-AB273
Hauptverfasser: Wheeler, Justin C., MD, Wu, David, PhD, Rothenberg, Marc E., MD, PhD, FAAAAI, Mukkada, Vincent A., MD, Hogan, Simon P., PhD
Format: Artikel
Sprache:eng
Schlagworte:
Allergy and Immunology
Esophagus
Gene expression
Small intestine
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Zusammenfassung:The effect of 17-beta estradiol (E2) in esophageal epithelial cell barrier function was examined, aiming to demonstrate E2 promotes cellular and molecular protective effects in EoE relevant assays.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2016.12.879