Risk for Attacks in Hereditary Angioedema (HAE) Population Correlates with C1-inhibitor Functional Activity (C1-INHact)

Methods Data from the COMPACT (Clinical Studies for Optimal Management in Preventing Angioedema with Low-Volume Subcutaneous C1-inhibitor Replacement Therapy) program were used to develop population PK (POPPK) and pharmacokinetic-pharmacodynamics (PK/PD) models.

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Veröffentlicht in:Journal of allergy and clinical immunology 2017-02, Vol.139 (2), p.AB233-AB233
Hauptverfasser: Cicardi, Marco, Li, Huamin Henry, MD, PhD, FAAAAI, Chase, Chevy, MD, Anderson, John T., MD, Bernstein, Jonathan A., MD, FAAAAI, Farkas, Henriette, Zhang, Ying, PhD, Pawaskar, Dipti, Pragst, Ingo, PhD
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Sprache:eng
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Zusammenfassung:Methods Data from the COMPACT (Clinical Studies for Optimal Management in Preventing Angioedema with Low-Volume Subcutaneous C1-inhibitor Replacement Therapy) program were used to develop population PK (POPPK) and pharmacokinetic-pharmacodynamics (PK/PD) models.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2016.12.750