Role of [alpha]7-nicotinic acetylcholine receptors of B cells in the immunotoxic effect of organophosphorus compounds

Experiments on white non-inbred rats demonstrated that treatment with organophosphorus compound dimethyl dichlorovinyl phosphate (DDVP) decreased T cell-independent antibody production by B cells and blood levels of IL-10 and IL-12; a similar effect was produced by GTS-21, a selective agonist of [al...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2016-10, Vol.161 (6), p.779
Hauptverfasser:	Zabrodskii, P.F, Maslyakov, V.V, Gromov, M.S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal experimentation Antibodies B cells Organic phosphorus compounds Poisoning T cells
Online-Zugang:	Volltext
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