Front Cover: 1‐Hydrosilatrane: A Locomotive for Efficient Ketone Reductions (Eur. J. Org. Chem. 2/2017)

The cover picture shows artist Jesse Mai's imagination of the reduction of ketones to alcohols by 1‐hydrosilatrane. The accompanying work describes this mild method for reduction, which makes use of a cheap, safe, easy‐to‐handle, and environmentally friendly silane reducing reagent. The reporte...

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Veröffentlicht in:European journal of organic chemistry 2017-01, Vol.2017 (2), p.208-208
Hauptverfasser: Varjosaari, Sami E., Skrypai, Vladislav, Suating, Paolo, Hurley, Joseph J. M., Gilbert, Thomas M., Adler, Marc J.
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Sprache:eng
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Zusammenfassung:The cover picture shows artist Jesse Mai's imagination of the reduction of ketones to alcohols by 1‐hydrosilatrane. The accompanying work describes this mild method for reduction, which makes use of a cheap, safe, easy‐to‐handle, and environmentally friendly silane reducing reagent. The reported results include the conversion of a wide scope of ketones to alcohols, as well as demonstrations of stereoselective reductions: the diastereoselective reduction of (–)‐menthone to (+)‐neomenthol and the reduction of a prochiral ketone to an alcohol with an enantiomeric ratio of 87:13. Details are discussed in the Communication by M. J. Adler et al. on page 229 ff (DOI: 10.1002/ejoc.201601256).
ISSN:1434-193X
1099-0690
DOI:10.1002/ejoc.201601660