Oxidative status of the myocardium in response to different intensities of physical training

Oxidative status of the myocardium in response to different intensities of physical training

The intensity of exercise determines the metabolic pathway and the energetic substrate that is spent. Our study sought to identify the effects of different intensities of swimming on myocardial oxidative status and the blood lipid profile. Eighty Wistar rats (male and female) submitted to different...

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Veröffentlicht in:Physiological research 2016-01, Vol.65 (5), p.737-749
Hauptverfasser: Guerreiro, L F, Rocha, A M, Martins, C N, Ribeiro, J P, Wally, C, Strieder, D L, Carissimi, C G, Oliveira, M G, Pereira, A A, Biondi, H S, Monserrat, J M, Gonçalves, C An
Format: Artikel
Sprache:eng
Schlagworte:
Adaptation
Animals
Antioxidants
Atherosclerosis
Exercise intensity
Female
Females
Fitness training programs
Heart attacks
Laboratory animals
Lipid Metabolism
Lipid peroxidation
Lipids
Male
Males
Metabolism
Mortality
Myocardium - metabolism
Oxidative stress
Physical Conditioning, Animal - physiology
Physical fitness
Physiology
Rats, Wistar
Reactive Oxygen Species - blood
Rodents
Studies
Workloads
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Zusammenfassung:The intensity of exercise determines the metabolic pathway and the energetic substrate that is spent. Our study sought to identify the effects of different intensities of swimming on myocardial oxidative status and the blood lipid profile. Eighty Wistar rats (male and female) submitted to different intensities of a swimming regimen (low, LS; moderate, MS; or high, HS) for 16 weeks. Samples of blood and myocardium from the left ventricle were collected to determine lipid profiles and oxidative status. Reactive oxygen species (ROS) and antioxidant capacity against peroxyl radicals (ACAP), lipid profiles and lipid peroxidation was analyzed. ROS levels and ACAP were higher in male rats than in female rats overall (p
ISSN:0862-8408
1802-9973
DOI:10.33549/physiolres.933185