Analysis of indel variations in the human disease-associated genes CDKN2AIP, WDR66, USP20 and OR7C2 in a Korean population

Recently, the human genes CDKN2AIP, WDR66, USP20 and OR7C2 have emerged as important genetic factors that could be biologically associated with cancer, haematological diseases and olfactory dysfunction. In this regard, analysis of indel (insertiondeletion) variations in these genes at a population scale is of signicant interest. In this study, we performed PCR amplications and sequencing of the loci of these four genes using genomic DNA from 100 Korean individuals. We analysed the indels in these genes and made predictions about the functional consequences that are likely caused by the indels.