A case report for three different malignancies in one patient

Introduction: The occurrence of multiple primary cancers (MPC) is rare. Only a few cases and patient reviews of an association of triple malignancy have been reported. Case presentation: We report here a case of a 56-year-old Saudi woman attended initially to us in 2012 as a case of breast cancer with a history of renal cell carcinoma treated in 2005. Our patient was treated with surgery for renal cell carcinoma and remained in good control for 7 years, when she developed a left breast mass and by work up she was diagnosed as a case of left breast cancer which was later treated by surgery and chemotherapy, and also because of the presence of rectal thickness in her work up which was confirmed by PET-CT, she also underwent colonoscopy with biopsy which confirmed as a rectal adenocarcinoma of primary Lower GIT origin which was later treated by surgery. Conclusion: Although the association of MPC can be considered a rare occurrence, improving survival in cancer patients has made this situation more frequent.