Tumor lysis syndrome and metastatic melanoma
Tumor lysis syndrome (TLS) is a potential emergent complication of oncologic treatment. TLS is commonly reported in hematological malignancies with rapid cell turnover rates, but is relatively rare in solid tumors. TLS is most frequently a result of cancer treatment in combination with a large tumor...
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Veröffentlicht in: | Medical oncology (Northwood, London, England) London, England), 2016-12, Vol.33 (12), p.134, Article 134 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Tumor lysis syndrome (TLS) is a potential emergent complication of oncologic treatment. TLS is commonly reported in hematological malignancies with rapid cell turnover rates, but is relatively rare in solid tumors. TLS is most frequently a result of cancer treatment in combination with a large tumor burden, but has occasionally been reported to occur spontaneously, especially in cases of advanced or metastatic disease. In this article, we describe the case of a patient with newly diagnosed metastatic melanoma that developed TLS two days after initiation of corticosteroids. In addition, we present a brief literature review of melanoma-associated TLS and review the etiology, diagnosis, and management of TLS. |
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ISSN: | 1357-0560 1559-131X |
DOI: | 10.1007/s12032-016-0854-5 |