TCT-196 From Door to Balloon to Door to Unload: A Transcriptomic Analysis Identifies that Primary Unloading Globally Shifts Gene Expression and Preserves Mitochondrial Integrity within the Infarct Zone during the Acute Phase of AMI
Background We recently reported that compared to Primary Reperfusion (PR), first reducing myocardial oxygen demand by activating an acute mechanical circulatory support (AMCS) pump while delaying coronary reperfusion (Primary Unloading; PU) reduces myocardial damage in models of acute myocardial inf...
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| Veröffentlicht in: | Journal of the American College of Cardiology 2016-11, Vol.68 (18), p.B80-B80 |
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| container_title | Journal of the American College of Cardiology |
| container_volume | 68 |
| creator | Esposito, Michele Zhang, Yali Schnitzler, Gavin Paruchuri, Vikram Qiao, Xiaoying Annamalai, Shiva Mackey, Emily Morine, Kevin Mullin, Andrew Breton, Catalina Karas, Richard Josephy, Noam Kapur, Navin |
| description | Background We recently reported that compared to Primary Reperfusion (PR), first reducing myocardial oxygen demand by activating an acute mechanical circulatory support (AMCS) pump while delaying coronary reperfusion (Primary Unloading; PU) reduces myocardial damage in models of acute myocardial infarction (AMI). |
| doi_str_mv | 10.1016/j.jacc.2016.09.338 |
| format | Article |
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Zhang, Yali ; Schnitzler, Gavin ; Paruchuri, Vikram ; Qiao, Xiaoying ; Annamalai, Shiva ; Mackey, Emily ; Morine, Kevin ; Mullin, Andrew ; Breton, Catalina ; Karas, Richard ; Josephy, Noam ; Kapur, Navin</creator><creatorcontrib>Esposito, Michele ; Zhang, Yali ; Schnitzler, Gavin ; Paruchuri, Vikram ; Qiao, Xiaoying ; Annamalai, Shiva ; Mackey, Emily ; Morine, Kevin ; Mullin, Andrew ; Breton, Catalina ; Karas, Richard ; Josephy, Noam ; Kapur, Navin</creatorcontrib><description>Background We recently reported that compared to Primary Reperfusion (PR), first reducing myocardial oxygen demand by activating an acute mechanical circulatory support (AMCS) pump while delaying coronary reperfusion (Primary Unloading; PU) reduces myocardial damage in models of acute myocardial infarction (AMI).</description><identifier>ISSN: 0735-1097</identifier><identifier>EISSN: 1558-3597</identifier><identifier>DOI: 10.1016/j.jacc.2016.09.338</identifier><language>eng</language><publisher>New York: Elsevier Inc</publisher><subject>Cardiology ; 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| ispartof | Journal of the American College of Cardiology, 2016-11, Vol.68 (18), p.B80-B80 |
| issn | 0735-1097 1558-3597 |
| language | eng |
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| source | Elsevier ScienceDirect Journals Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Cardiology Cardiovascular Gene expression Internal Medicine Scanning electron microscopy |
| title | TCT-196 From Door to Balloon to Door to Unload: A Transcriptomic Analysis Identifies that Primary Unloading Globally Shifts Gene Expression and Preserves Mitochondrial Integrity within the Infarct Zone during the Acute Phase of AMI |
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