Assessing the Reliability of the Default Mode Network (DMN) using the Intra-Class Correlation Coefficient

The ICC reflects the ratio between intra-subject variance (between-subjects minus the error sums of squares) and the total variance (between-subjects plus the error sums of squares). [...]high ICC reflect less variable correlation strength across sessions than across subjects. Results We found a distributed network of brain areas, consistent with the "default mode" network, was significantly correlated with the seed regions in all three cases (LP, PCC, MPF seeds, see Figure 1).