Amygdala activation is associated with prefrontal cortical thickness in healthy subjects, but not in euthymic bipolar patients

Amygdala activation is associated with prefrontal cortical thickness in healthy subjects, but not in euthymic bipolar patients

Conclusions This is the first study to demonstrate that, in healthy subjects, gray matter thickness in right PFC is negatively associated with activation level of the amygdala. [...]the amount of gray matter volume in PFC may be directly related to this region's ability to modulate or inhibit a...

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Veröffentlicht in:NeuroImage (Orlando, Fla.) Fla.), 2009-07, Vol.47, p.S181-S181
Hauptverfasser: Foland-Ross, LC, Thompson, PM, Bookheimer, SY, Penfold, C, Shen, JK, Ahlf, K, Madsen, S, Townsend, J, Fischer, J, Altshuler, LL
Format: Artikel
Sprache:eng
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Zusammenfassung:Conclusions This is the first study to demonstrate that, in healthy subjects, gray matter thickness in right PFC is negatively associated with activation level of the amygdala. [...]the amount of gray matter volume in PFC may be directly related to this region's ability to modulate or inhibit activation in the amygdala.
ISSN:1053-8119
1095-9572
DOI:10.1016/S1053-8119(09)71992-5