Propofol Sedation Attenuates Resting-State Connectivity in the Salience Network

Propofol Sedation Attenuates Resting-State Connectivity in the Salience Network

Methods Nineteen healthy right-handed subjects provided written informed consent and underwent resting-state fMRI scans during wakefulness, light sedation (Ramsay 3), deep sedation (Ramsay 5), and recovery. In the remaining 17 subjects we calculated one-sample t-tests of the salience network separat...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:NeuroImage (Orlando, Fla.) Fla.), 2009-07, Vol.47, p.S193-S193
Hauptverfasser: Boveroux, P, Boly, M, Mackey, S, Dixit, R, Laureys, S, Greicius, M
Format: Artikel
Sprache:eng
Schlagworte:
Anesthesia
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Methods Nineteen healthy right-handed subjects provided written informed consent and underwent resting-state fMRI scans during wakefulness, light sedation (Ramsay 3), deep sedation (Ramsay 5), and recovery. In the remaining 17 subjects we calculated one-sample t-tests of the salience network separately for wakefulness and deep sedation and a paired t-test directly contrasting salience network connectivity in the two states.
ISSN:1053-8119
1095-9572
DOI:10.1016/S1053-8119(09)72170-6