Genetic polymorphisms in CRHR1 and CRHR2 associated with BOLD activity in response to emotional faces in insula, amygdala and caudate

Genetic polymorphisms in CRHR1 and CRHR2 associated with BOLD activity in response to emotional faces in insula, amygdala and caudate

A separate regression analysis revealed that subjects with 1 (n=25) or 2 (n=4) copies of the C allele at the rs2190242 SNP in CRHR2 had significantly greater activation to emotional face stimuli in bilateral caudate and in the left amygdala compared to subjects homozygous for the A allele (n=29; see...

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Veröffentlicht in:NeuroImage (Orlando, Fla.) Fla.), 2009-07, Vol.47, p.S140-S140
Hauptverfasser: Tankersley, D, Stein, MB, Frihauf, J, Gelernter, J, Paulus, MP
Format: Artikel
Sprache:eng
Schlagworte:
Anxiety
Genes
Polymorphism
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Zusammenfassung:A separate regression analysis revealed that subjects with 1 (n=25) or 2 (n=4) copies of the C allele at the rs2190242 SNP in CRHR2 had significantly greater activation to emotional face stimuli in bilateral caudate and in the left amygdala compared to subjects homozygous for the A allele (n=29; see Figure 2).
ISSN:1053-8119
1095-9572
DOI:10.1016/S1053-8119(09)71390-4